RE: Appendiceal Immunoglobulin G4-Related Disease Mimicking Appendiceal Tumor or Appendicitis: A Case Report

We read with great interest the article by Kim et al. (1), titled “Appendiceal immunoglobulin G4-related disease mimicking appendiceal tumor or appendicitis: a case report,” that described the first report of immunoglobulin G4 (IgG4)-related disease involving appendix. The authors emphasized the significance of recognizing this relatively recent entity in the differential diagnosis for a massforming lesion to avoid unnecessary surgery. We encountered a similar scenario, in which a patient was presented with signs and symptoms of appendicitis, accompanied by a mass-forming lesion. This raised a clinical concern of neoplasm, therefore hemicolectomy was conducted as a curative option. Upon pathological evaluation, the lesion revealed a chronic fibro-inflammatory process with lymphoplasmacytic infiltrate of which, the IgG4 subset accounted for > 50 percent overall and > 100/ high power field in high density areas accompanied by Letter to the Editor